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despicably (adv)
despise (v)
despised (adj)
despite (prep)
despoil (v)
despoilment (n)
despoliation (n)
despondency (n)
despondent (adj)
despondently (adv)
despot (n)
despotic (adj)
despotically (adv)
despotism (n)
dessert (n)
dessert (types of)
destabilization (n)
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despondent (adj)

Synonymshopeless, low, dejected, despairing, downhearted, downcast, unhappy, sad, pessimistic, miserable, glum, discouraged

Antonymcheerful

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